"Program" se refere ao programa de computador, ou seja, é mais usado no mundo do TI:
This computer program needs
to be reinstaled right away!
"Programme" é
quando nos referimos aos programas de televisão ou algum treinamento:
Oh please, turn it off!
This TV programme is really awful!
I'll talk to my teacher
because I'd like to change my training programmes. I need to work my shoulders
out.
That's all for now, guys!
Stay tuned for more hints!